The four biggest variables affecting a program's IVF success rates:

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• The quality of the laboratory environment and the skill of the embryology staff
• The skill and experience of the reproductive endocrinologist doctor (fertility specialist)
• The average number of embryos transferred per case
• If donor eggs are being used, IVF rates will be higher
• How "success" is measured eg: number of live births, number of positive pregnancy results etc..

Some clinics push their in vitro fertilization success rates up by transferring high numbers of embryos. Whether this is good or bad for an individual couple depends on whether the couple conceives, and if so - how many fetuses have implanted in the uterus.
A clinic with a policy to transfer a high numbers of embryos may have a high overall success rate, but will be likely to have a high rate of triplet or quadruplet pregnancies. These are very high risk pregnancies for the babies.
Triplet pregnancies should be prevented as much as possible. About 10-15% of triplet pregnancies (without fetal reduction) will result in delivery so early that there are no living children to take home from the hospital. In some other cases, the babies will survive but have long-term handicaps such as cerebral palsy or mental retardation. For quadruplets the risks are even higher.


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