Radiesse patients reported the highest level of satisfaction

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Dermatologic Surgery published an article regarding a comparative study between major dermal fillers available in the US market. These fillers included Juvéderm, Juvéderm ULTRA, Perlane, and Radiesse. This study benefits patients concerned about which filler would probably be best for their personal use and can also help physicians assist their patients in that choice process. For the study, two standardized scales were used to make their assessments on the products. One is the Global Aesthetic Improvement Scale (GAIS) and the other is the Wrinkle Severity Rating Scale (WSRS).

The rising popularity in dermal fillers has raised questions from both patients and physicians. The study was designed to help patients and physicians make wiser choices on fillers for the best results with the least overall expense. A panel of 205 patients between the ages of 18 - 80 years of age (52 being the median) were randomly administered an adequate amount of an undisclosed dermal filler (Radiesse, Juvéderm, Juvéderm ULTRA, or Perlane) to produce the fullest result. They were then asked to return for a touch up in 4 months. After touch up they were to return at 4, 8, and 12 months after for reevaluation.


By the touch up date (4 months after initial treatment) all patients received a touch and discussed their satisfaction of the results before reapplication. Of the 4 filler types, Radiesse patients reported the highest level of satisfaction. Juvéderm at this stage received the lowest mark.

At the 4 and 8 month reevaluation periods, all patients administered Radiesse had reported nearly the same level of satisfaction with their results. Perlane and Juvéderm ULTRA did better by this point while Juvéderm required reapplication in most patients. By 12 months, Radiesse had the highest patient satisfaction with the least application. Juvéderm received the lowest with the highest reapplication.

Patient satisfaction is based on the overall visibility of the patient's Nasolabial Folds (NLFs). All products used did exactly what they were designed for. Some required more of the product to achieve adequate fullness. This is a briefing of the products and median amount used per patient:


o Juvéderm - 8 Syringes
o Juvéderm ULTRA - 4 Syringes
o Perlane - 3 Syringes
o Radiesse - 2 Syringes

When considering cosmetic surgery or cosmetic treatment, you should always take into account overall effectiveness instead of initial expense. You may find yourself achieving your goals with less work resulting in lower overall expense. Juvéderm is an effective product and may perform better on other areas. Radiesse is also a resilient dermal filler and one of few
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recommended for patients suffering from HIV-associated facial lipoatrophy.

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