Always follow the instructions on the manufacturer's bra label.
If manufacture labels are not present, always wash bras carefully by hand. Always use cold water and a light gentle hand soap or very mild detergent on the bra.
Drip dry bras or dry on a flat surface if possible.
Do not machine wash your bras! If you must wash your bras in a washer: Use a delicate cycle in cold water only, and separate the colors when washing your bras. Fasten all hooks and place bras in a (Wash) lingerie bag if possible.
Do not put bras in the dryer! If you must, tumble dry on a low setting with bras still in the lingerie bag.
Wash bras at least every other wearing to reduce discoloration and damage from body oils.
Wear bras in rotation. If you find a bra that you love, buy several bras the same size. Bra manufacturers frequently discontinue styles.
Do not overwear your bra. The bra will loose the form and structure.
Signs of an overworn bra include: wrinkles in bra cup, rides up back, or slips off the shoulders.
Replace bras at least every two years.
As with anything, the quality of bras can differ by brand. Make sure to shop a variety of brands to get the best fit for your breast type.
Tiffany Hart writes an online bra guide for DivaBras.com – a site catering to women in need of plus size bras.