When few or no ancestors are common to the sire and dam, the breeding is known as an outcross. Some outcrosses are excellent, while others are not. Puppies can resemble the sire, the dam, or a combination of the parents or even a remote ancestor.
Line breeding is generally the safest course to practice when both the sire and the dam of the litter share multiple common ancestors. You work with known qualities. With line breeding you will know in advance to some degree what the puppies will look like and how they most likely will behave.
Inbreeding is the most misunderstood of all the breeding formulas and should be done by only the most experienced breeders, those who have a very strong grasp of genetics and who have known the direct ancestors for at least the first few generations. Type is firmly set by inbreeding. Good or poor qualities are intensified. There is the opportunity to produce superior puppies, but there is also the risk of producing very poor specimens. The best and worst of the ancestors should be carefully evaluated before using the inbreeding formula.
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